| Reaction Details |
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 | Report a problem with these data |
| Target | Mitochondrial 2-oxodicarboxylate carrier |
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| Ligand | BDBM50028197 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2015975 (CHEMBL4669553) |
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| IC50 | 252000±n/a nM |
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| Citation |  Schultz, CR; Gruhlke, MCH; Slusarenko, AJ; Bachmann, AS Allicin, a Potent New Ornithine Decarboxylase Inhibitor in Neuroblastoma Cells. J Nat Prod83:2518-2527 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mitochondrial 2-oxodicarboxylate carrier |
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| Name: | Mitochondrial 2-oxodicarboxylate carrier |
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| Synonyms: | Mitochondrial 2-oxodicarboxylate carrier | ODC | ODC_HUMAN | SLC25A21 | Solute carrier family 25 member 21 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 33315.79 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_120108 |
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| Residue: | 299 |
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| Sequence: | MSAKPEVSLVREASRQIVAGGSAGLVEICLMHPLDVVKTRFQIQRCATDPNSYKSLVDSF
RMIFQMEGLFGFYKGILPPILAETPKRAVKFFTFEQYKKLLGYVSLSPALTFAIAGLGSG
LTEAIVVNPFEVVKVGLQANRNTFAEQPSTVGYARQIIKKEGWGLQGLNKGLTATLGRHG
VFNMVYFGFYYNVKNMIPVNKDPILEFWRKFGIGLLSGTIASVINIPFDVAKSRIQGPQP
VPGEIKYRTCFKTMATVYQEEGILALYKGLLPKIMRLGPGGAVMLLVYEYTYSWLQENW
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| BDBM50028197 |
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| n/a |
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| Name | BDBM50028197 |
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| Synonyms: | 2-(difluoromethyl)ornithine | CHEMBL830 | EFLORNITHINE |
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| Type | Small organic molecule |
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| Emp. Form. | C6H12F2N2O2 |
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| Mol. Mass. | 182.1685 |
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| SMILES | NCCCC(N)(C(F)F)C(O)=O |
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| Structure | 
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