| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 4 |
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| Ligand | BDBM50105652 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_3346 (CHEMBL619046) |
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| Ki | 48±n/a nM |
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| Citation |  López-Rodríguez, ML; Murcia, M; Benhamú, B; Viso, A; Campillo, M; Pardo, L 3-D-QSAR/CoMFA and recognition models of benzimidazole derivatives at the 5-HT(4) receptor. Bioorg Med Chem Lett11:2807-11 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 4 |
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| Name: | 5-hydroxytryptamine receptor 4 |
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| Synonyms: | 5-HT-4 | 5-HT4 | 5-HT4L | 5-HT4S | 5-hydroxytryptamine receptor 4 | 5HT4R_RAT | Htr4 | Serotonin (5-HT) receptor | Serotonin 4 (5-HT4) receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 46117.31 |
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| Organism: | RAT |
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| Description: | 5-HT4 HTR4 RAT::Q62758 |
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| Residue: | 406 |
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| Sequence: | MDRLDANVSSNEGFGSVEKVVLLTFFAMVILMAILGNLLVMVAVCRDRQLRKIKTNYFIV
SLAFADLLVSVLVNAFGAIELVQDIWFYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYY
AICCQPLVYRNKMTPLRIALMLGGCWVIPMFISFLPIMQGWNNIGIVDVIEKRKFNHNSN
STFCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRP
QTADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEKVWTAFLWL
GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRD
TVECGGQWESRCHLTATSPLVAAQPVIRRPQDNDLEDSCSLKRSQS
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| BDBM50105652 |
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| n/a |
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| Name | BDBM50105652 |
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| Synonyms: | 6-Bromo-7-nitro-1H-benzoimidazole-4-carboxylic acid (1-butyl-piperidin-4-ylmethyl)-amide | CHEMBL329545 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H24BrN5O3 |
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| Mol. Mass. | 438.319 |
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| SMILES | CCCCN1CCC(CNC(=O)c2cc(Br)c([N+]([O-])=O)c3nc[nH]c23)CC1 |
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| Structure | 
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