| Reaction Details |
|---|
 | Report a problem with these data |
| Target | G-protein coupled receptor 84 |
|---|
| Ligand | BDBM50548412 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2022125 (CHEMBL4675938) |
|---|
| IC50 | 11±n/a nM |
|---|
| Citation |  Labéguère, F; Dupont, S; Alvey, L; Soulas, F; Newsome, G; Tirera, A; Quenehen, V; Mai, TTT; Deprez, P; Blanqué, R; Oste, L; Le Tallec, S; De Vos, S; Hagers, A; Vandevelde, A; Nelles, L; Vandervoort, N; Conrath, K; Christophe, T; van der Aar, E; Wakselman, E; Merciris, D; Cottereaux, C; da Costa, C; Saniere, L; Clement-Lacroix, P; Jenkins, L; Milligan, G; Fletcher, S; Brys, R; Gosmini, R Discovery of 9-Cyclopropylethynyl-2-(( J Med Chem63:13526-13545 (2020) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| G-protein coupled receptor 84 |
|---|
| Name: | G-protein coupled receptor 84 |
|---|
| Synonyms: | EX33 | G-protein coupled receptor 84 | GPR84 | GPR84_HUMAN | Inflammation-related G-protein coupled receptor EX33 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 43726.73 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_116040 |
|---|
| Residue: | 396 |
|---|
| Sequence: | MWNSSDANFSCYHESVLGYRYVAVSWGVVVAVTGTVGNVLTLLALAIQPKLRTRFNLLIA
NLTLADLLYCTLLQPFSVDTYLHLHWRTGATFCRVFGLLLFASNSVSILTLCLIALGRYL
LIAHPKLFPQVFSAKGIVLALVSTWVVGVASFAPLWPIYILVPVVCTCSFDRIRGRPYTT
ILMGIYFVLGLSSVGIFYCLIHRQVKRAAQALDQYKLRQASIHSNHVARTDEAMPGRFQE
LDSRLASGGPSEGISSEPVSAATTQTLEGDSSEVGDQINSKRAKQMAEKSPPEASAKAQP
IKGARRAPDSSSEFGKVTRMCFAVFLCFALSYIPFLLLNILDARVQAPRVVHMLAANLTW
LNGCINPVLYAAMNRQFRQAYGSILKRGPRSFHRLH
|
|
|
|---|
| BDBM50548412 |
|---|
| n/a |
|---|
| Name | BDBM50548412 |
|---|
| Synonyms: | CHEMBL4776061 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H21N3O5 |
|---|
| Mol. Mass. | 395.4085 |
|---|
| SMILES | COc1cc2CCn3c(cc(OCCOc4ccccn4)nc3=O)-c2cc1OC |
|---|
| Structure | 
|
|---|
Search and Browse
