| Reaction Details |
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 | Report a problem with these data |
| Target | D(3) dopamine receptor |
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| Ligand | BDBM50107880 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_62758 (CHEMBL676127) |
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| Ki | 136±n/a nM |
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| Citation |  Haadsma-Svensson, SR; Cleek, KA; Dinh, DM; Duncan, JN; Haber, CL; Huff, RM; Lajiness, ME; Nichols, NF; Smith, MW; Svensson, KA; Zaya, MJ; Carlsson, A; Lin, CH Dopamine D(3) receptor antagonists. 1. Synthesis and structure-activity relationships of 5,6-dimethoxy-N-alkyl- and N-alkylaryl-substituted 2-aminoindans. J Med Chem44:4716-32 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(3) dopamine receptor |
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| Name: | D(3) dopamine receptor |
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| Synonyms: | DOPAMINE D3 | DRD3_RAT | Dopamine D3 receptor | Drd3 |
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| Type: | Protein |
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| Mol. Mass.: | 49540.58 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P19020 |
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| Residue: | 446 |
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| Sequence: | MAPLSQISTHLNSTCGAENSTGVNRARPHAYYALSYCALILAIIFGNGLVCAAVLRERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPSI
CSISNPDFVIYSSVVSFYVPFGVTVLVYARIYIVLRQRQRKRILTRQNSQCISIRPGFPQ
QSSCLRLHPIRQFSIRARFLSDATGQMEHIEDKQYPQKCQDPLLSHLQPPSPGQTHGGLK
RYYSICQDTALRHPSLEGGAGMSPVERTRNSLSPTMAPKLSLEVRKLSNGRLSTSLRLGP
LQPRGVPLREKKATQMVVIVLGAFIVCWLPFFLTHVLNTHCQACHVSPELYRATTWLGYV
NSALNPVIYTTFNVEFRKAFLKILSC
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| BDBM50107880 |
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| n/a |
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| Name | BDBM50107880 |
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| Synonyms: | 4-{2-[(5,6-Dimethoxy-indan-2-yl)-propyl-amino]-ethyl}-thiazol-2-ylamine | CHEMBL141614 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H27N3O2S |
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| Mol. Mass. | 361.502 |
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| SMILES | CCCN(CCc1csc(N)n1)C1Cc2cc(OC)c(OC)cc2C1 |
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| Structure | 
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