| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Excitatory amino acid transporter 3 |
|---|
| Ligand | BDBM50107947 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_68330 (CHEMBL680701) |
|---|
| IC50 | >1000000±n/a nM |
|---|
| Citation |  Stensbøl, TB; Uhlmann, P; Morel, S; Eriksen, BL; Felding, J; Kromann, H; Hermit, MB; Greenwood, JR; Braüner-Osborne, H; Madsen, U; Junager, F; Krogsgaard-Larsen, P; Begtrup, M; Vedsø, P Novel 1-hydroxyazole bioisosteres of glutamic acid. Synthesis, protolytic properties, and pharmacology. J Med Chem45:19-31 (2001) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Excitatory amino acid transporter 3 |
|---|
| Name: | Excitatory amino acid transporter 3 |
|---|
| Synonyms: | EAA3_HUMAN | EAAC1 | EAAT3 | Excitatory Amino Acid EAAT3 | HEAAC1 | SLC1A1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 57096.71 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Excitatory Amino Acid EAAT3 0 HUMAN::P43005 |
|---|
| Residue: | 524 |
|---|
| Sequence: | MGKPARKGCEWKRFLKNNWVLLSTVAAVVLGITTGVLVREHSNLSTLEKFYFAFPGEILM
RMLKLIILPLIISSMITGVAALDSNVSGKIGLRAVVYYFCTTLIAVILGIVLVVSIKPGV
TQKVGEIARTGSTPEVSTVDAMLDLIRNMFPENLVQACFQQYKTKREEVKPPSDPEMNMT
EESFTAVMTTAISKNKTKEYKIVGMYSDGINVLGLIVFCLVFGLVIGKMGEKGQILVDFF
NALSDATMKIVQIIMCYMPLGILFLIAGKIIEVEDWEIFRKLGLYMATVLTGLAIHSIVI
LPLIYFIVVRKNPFRFAMGMAQALLTALMISSSSATLPVTFRCAEENNQVDKRITRFVLP
VGATINMDGTALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGAAGVPQAGLVTMV
IVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKKELEQMDVSSEVN
IVNPFALESTILDNEDSDTKKSYVNGGFAVDKSDTISFTQTSQF
|
|
|
|---|
| BDBM50107947 |
|---|
| n/a |
|---|
| Name | BDBM50107947 |
|---|
| Synonyms: | 2-Amino-3-(1-hydroxy-5-methyl-1H-imidazol-2-yl)-propionic acid | CHEMBL104039 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C7H11N3O3 |
|---|
| Mol. Mass. | 185.1805 |
|---|
| SMILES | Cc1cnc(CC(N)C(O)=O)n1O |
|---|
| Structure | 
|
|---|
Search and Browse
