Reaction Details | |||
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Target | Indoleamine 2,3-dioxygenase 1 | ||
Ligand | BDBM50549535 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_2025270 (CHEMBL4679083) | ||
IC50 | 7.8±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Indoleamine 2,3-dioxygenase 1 | |||
Name: | Indoleamine 2,3-dioxygenase 1 | ||
Synonyms: | I23O1_MOUSE | IDO-1 | Ido | Ido1 | Indo | Indoleamine-pyrrole 2,3-dioxygenase | ||
Type: | PROTEIN | ||
Mol. Mass.: | 45639.39 | ||
Organism: | Mus musculus | ||
Description: | ChEMBL_1452149 | ||
Residue: | 407 | ||
Sequence: |
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BDBM50549535 | |||
n/a | |||
Name | BDBM50549535 | ||
Synonyms: | CHEMBL4763375 | ||
Type | Small organic molecule | ||
Emp. Form. | C23H23ClF3NO2 | ||
Mol. Mass. | 437.882 | ||
SMILES | [H][C@@]1(CC[C@@]2(COc3cc(ccc23)C(F)(F)F)CC1)[C@H](C)C(=O)Nc1ccc(Cl)cc1 |r,wU:4.4,19.22,wD:1.0,(49.52,-49.21,;49.47,-50.71,;50.8,-49.93,;52.14,-50.7,;52.14,-52.25,;53.43,-51.41,;54.62,-52.38,;54.07,-53.81,;54.76,-55.17,;53.93,-56.45,;52.39,-56.37,;51.7,-55,;52.54,-53.72,;54.62,-57.81,;55.95,-57.04,;55.96,-58.58,;53.79,-59.11,;50.8,-53.03,;49.47,-52.25,;48.13,-49.95,;48.12,-48.41,;46.79,-50.72,;46.79,-52.27,;45.45,-49.96,;44.12,-50.73,;44.12,-52.29,;42.78,-53.07,;41.44,-52.29,;40.1,-53.06,;41.44,-50.74,;42.77,-49.97,)| | ||
Structure | ![]() |