Reaction Details | |||
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Target | Indoleamine 2,3-dioxygenase 1 | ||
Ligand | BDBM50549537 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_2025273 (CHEMBL4679086) | ||
IC50 | 320±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Indoleamine 2,3-dioxygenase 1 | |||
Name: | Indoleamine 2,3-dioxygenase 1 | ||
Synonyms: | I23O1_HUMAN | IDO | IDO-1 | IDO1 | INDO | Indoleamine 2,3-Dioxygenasae (IDO) | Indoleamine 2,3-dioxygenase | Indoleamine-pyrrole 2,3-dioxygenase | ||
Type: | Enzyme | ||
Mol. Mass.: | 45330.80 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P14902 | ||
Residue: | 403 | ||
Sequence: |
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BDBM50549537 | |||
n/a | |||
Name | BDBM50549537 | ||
Synonyms: | CHEMBL4761104 | ||
Type | Small organic molecule | ||
Emp. Form. | C23H24ClF3N2O2 | ||
Mol. Mass. | 452.897 | ||
SMILES | [H][C@@]1(CC[C@@]2(COc3cc(ccc23)C(F)(F)F)CC1)[C@H](CC)C(=O)Nc1ccc(Cl)cn1 |r,wU:4.4,19.22,wD:1.0,(11.99,-3.45,;11.89,-5.07,;13.22,-4.29,;14.57,-5.06,;14.56,-6.6,;15.85,-5.77,;17.05,-6.74,;16.49,-8.17,;17.18,-9.53,;16.35,-10.81,;14.81,-10.73,;14.12,-9.36,;14.96,-8.08,;17.05,-12.18,;18.38,-11.4,;18.39,-12.94,;16.21,-13.48,;13.22,-7.38,;11.89,-6.61,;10.55,-4.3,;10.54,-2.76,;11.87,-1.99,;9.21,-5.08,;9.21,-6.62,;7.86,-4.31,;6.53,-5.09,;5.18,-4.32,;3.84,-5.09,;3.84,-6.65,;2.5,-7.42,;5.19,-7.42,;6.53,-6.65,)| | ||
Structure | ![]() |