Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Glutamate receptor ionotropic, kainate 1 | ||
| Ligand | BDBM50109657 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_90313 (CHEMBL698527) | ||
| IC50 | >100000±n/a nM | ||
| Citation |  Kromann, H; Sløk, FA; Stensbøl, TB; Bräuner-Osborne, H; Madsen, U; Krogsgaard-Larsen, P Selective antagonists at group I metabotropic glutamate receptors: synthesis and molecular pharmacology of 4-aryl-3-isoxazolol amino acids. J Med Chem45:988-91 (2002) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Glutamate receptor ionotropic, kainate 1 | |||
| Name: | Glutamate receptor ionotropic, kainate 1 | ||
| Synonyms: | GRIK1_RAT | Glur5 | Glutamate receptor ionotropic kainate 1 | Glutamate receptor ionotropic, kainate | Glutamate receptor, ionotropic kainate 1 | Glutamate-Kainate | Grik1 | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 107860.82 | ||
| Organism: | RAT | ||
| Description: | P22756 | ||
| Residue: | 949 | ||
| Sequence: |
| ||
| BDBM50109657 | |||
| n/a | |||
| Name | BDBM50109657 | ||
| Synonyms: | 2-Amino-3-[3-hydroxy-4-(2-hydroxy-phenyl)-isoxazol-5-yl]-propionic acid | CHEMBL368858 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C12H12N2O5 | ||
| Mol. Mass. | 264.2341 | ||
| SMILES | N[C@@H](Cc1o[nH]c(=O)c1-c1ccccc1O)C(O)=O |wD:1.0,(7.95,-7.83,;7.97,-6.31,;9.31,-5.54,;9.31,-3.99,;8.53,-2.66,;9.58,-1.52,;10.98,-2.15,;12.32,-1.39,;10.8,-3.68,;11.94,-4.72,;13.41,-4.24,;14.55,-5.26,;14.23,-6.78,;12.75,-7.25,;11.62,-6.22,;10.15,-6.69,;6.63,-5.54,;5.3,-6.31,;6.63,-3.99,)| | ||
| Structure | 
| ||