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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Glutamate receptor ionotropic, kainate 1 | ||
| Ligand | BDBM50109655 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_90313 (CHEMBL698527) | ||
| IC50 | >100000±n/a nM | ||
| Citation |  Kromann, H; Sløk, FA; Stensbøl, TB; Bräuner-Osborne, H; Madsen, U; Krogsgaard-Larsen, P Selective antagonists at group I metabotropic glutamate receptors: synthesis and molecular pharmacology of 4-aryl-3-isoxazolol amino acids. J Med Chem45:988-91 (2002) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Glutamate receptor ionotropic, kainate 1 | |||
| Name: | Glutamate receptor ionotropic, kainate 1 | ||
| Synonyms: | GRIK1_RAT | Glur5 | Glutamate receptor ionotropic kainate 1 | Glutamate receptor ionotropic, kainate | Glutamate receptor, ionotropic kainate 1 | Glutamate-Kainate | Grik1 | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 107860.82 | ||
| Organism: | RAT | ||
| Description: | P22756 | ||
| Residue: | 949 | ||
| Sequence: |
| ||
| BDBM50109655 | |||
| n/a | |||
| Name | BDBM50109655 | ||
| Synonyms: | 2-Amino-3-(3-hydroxy-4-naphthalen-1-yl-isoxazol-5-yl)-propionic acid | CHEMBL174625 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C16H14N2O4 | ||
| Mol. Mass. | 298.2934 | ||
| SMILES | N[C@@H](Cc1o[nH]c(=O)c1-c1cccc2ccccc12)C(O)=O |wD:1.0,(9.35,-10.71,;9.36,-9.17,;10.69,-8.4,;10.69,-6.86,;9.94,-5.53,;10.97,-4.38,;12.38,-5.01,;13.71,-4.24,;12.21,-6.55,;13.35,-7.58,;13.01,-9.08,;14.15,-10.12,;15.63,-9.66,;15.95,-8.14,;17.4,-7.68,;17.73,-6.17,;16.59,-5.14,;15.13,-5.61,;14.81,-7.11,;8.03,-8.4,;6.69,-9.17,;8.03,-6.86,)| | ||
| Structure | 
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