| Reaction Details |
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 | Report a problem with these data |
| Target | Steroid 17-alpha-hydroxylase/17,20 lyase |
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| Ligand | BDBM50318484 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2033579 (CHEMBL4687737) |
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| Ki | 124000±n/a nM |
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| Citation |  Nelson, KM; Bisson, J; Singh, G; Graham, JG; Chen, SN; Friesen, JB; Dahlin, JL; Niemitz, M; Walters, MA; Pauli, GF The Essential Medicinal Chemistry of Cannabidiol (CBD). J Med Chem63:12137-12155 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Steroid 17-alpha-hydroxylase/17,20 lyase |
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| Name: | Steroid 17-alpha-hydroxylase/17,20 lyase |
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| Synonyms: | CP17A_RAT | Cyp17 | Cyp17a1 | Cytochrome P450 17,20 lyase | Cytochrome P450 17A1 | Cytochrome P450-C17 | Steroid 17-alpha-hydroxylase/17,20 lyase |
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| Type: | Enzyme |
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| Mol. Mass.: | 57255.68 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P11715 |
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| Residue: | 507 |
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| Sequence: | MWELVGLLLLILAYFFWVKSKTPGAKLPRSLPSLPLVGSLPFLPRRGHMHVNFFKLQEKY
GPIYSLRLGTTTTVIIGHYQLAREVLIKKGKEFSGRPQMVTQSLLSDQGKGVAFADAGSS
WHLHRKLVFSTFSLFKDGQKLEKLICQEAKSLCDMMLAHDKESIDLSTPIFMSVTNIICA
ICFNISYEKNDPKLTAIKTFTEGIVDATGDRNLVDIFPWLTIFPNKGLEVIKGYAKVRNE
VLTGIFEKCREKFDSQSISSLTDILIQAKMNSDNNNSCEGRDPDVFSDRHILATVGDIFG
AGIETTTTVLKWILAFLVHNPEVKKKIQKEIDQYVGFSRTPTFNDRSHLLMLEATIREVL
RIRPVAPMLIPHKANVDSSIGEFTVPKDTHVVVNLWALHHDENEWDQPDQFMPERFLDPT
GSHLITPTQSYLPFGAGPRSCIGEALARQELFVFTALLLQRFDLDVSDDKQLPRLEGDPK
VVFLIDPFKVKITVRQAWMDAQAEVST
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| BDBM50318484 |
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| n/a |
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| Name | BDBM50318484 |
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| Synonyms: | 2-((1R,6R)-6-Isopropenyl-3-methyl-cyclohex-2-enyl)-5-pentyl-benzene-1,3-diol | CANNABIDIOL | CHEMBL190461 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H30O2 |
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| Mol. Mass. | 314.4617 |
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| SMILES | CCCCCc1cc(O)c([C@@H]2C=C(C)CC[C@H]2C(C)=C)c(O)c1 |r,t:11| |
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| Structure | 
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