| Reaction Details |
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 | Report a problem with these data |
| Target | Neutrophil collagenase |
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| Ligand | BDBM50112005 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_105204 |
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| Ki | 38000±n/a nM |
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| Citation |  Krumme, D; Tschesche, H Oxal hydroxamic acid derivatives with inhibitory activity against matrix metalloproteinases. Bioorg Med Chem Lett12:933-6 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Neutrophil collagenase |
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| Name: | Neutrophil collagenase |
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| Synonyms: | CLG1 | MMP-8 | MMP8 | MMP8_HUMAN | Matrix metalloproteinase-8 | Neutrophil collagenase precursor | PMNL collagenase | PMNL-CL |
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| Type: | Enzyme |
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| Mol. Mass.: | 53413.48 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P22894 |
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| Residue: | 467 |
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| Sequence: | MFSLKTLPFLLLLHVQISKAFPVSSKEKNTKTVQDYLEKFYQLPSNQYQSTRKNGTNVIV
EKLKEMQRFFGLNVTGKPNEETLDMMKKPRCGVPDSGGFMLTPGNPKWERTNLTYRIRNY
TPQLSEAEVERAIKDAFELWSVASPLIFTRISQGEADINIAFYQRDHGDNSPFDGPNGIL
AHAFQPGQGIGGDAHFDAEETWTNTSANYNLFLVAAHEFGHSLGLAHSSDPGALMYPNYA
FRETSNYSLPQDDIDGIQAIYGLSSNPIQPTGPSTPKPCDPSLTFDAITTLRGEILFFKD
RYFWRRHPQLQRVEMNFISLFWPSLPTGIQAAYEDFDRDLIFLFKGNQYWALSGYDILQG
YPKDISNYGFPSSVQAIDAAVFYRSKTYFFVNDQFWRYDNQRQFMEPGYPKSISGAFPGI
ESKVDAVFQQEHFFHVFSGPRYYAFDLIAQRVTRVARGNKWLNCRYG
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| BDBM50112005 |
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| n/a |
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| Name | BDBM50112005 |
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| Synonyms: | CHEMBL355756 | N-((S)-1-Dimethylcarbamoyl-2-phenyl-ethyl)-N'-hydroxy-oxalamide |
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| Type | Small organic molecule |
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| Emp. Form. | C13H17N3O4 |
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| Mol. Mass. | 279.2918 |
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| SMILES | CN(C)C(=O)[C@H](Cc1ccccc1)NC(=O)C(=O)NO |
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| Structure | 
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