| Reaction Details |
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 | Report a problem with these data |
| Target | Serine protease 1 |
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| Ligand | BDBM50112487 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_212328 |
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| Ki | 830±n/a nM |
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| Citation |  Wu, S; Guilford, WJ; Chou, YL; Griedel, BD; Liang, A; Sakata, S; Shaw, KJ; Trinh, L; Xu, W; Zhao, Z; Morrissey, MM Design and synthesis of aminophenol-based factor Xa inhibitors. Bioorg Med Chem Lett12:1307-10 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine protease 1 |
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| Name: | Serine protease 1 |
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| Synonyms: | Beta-Trypsin | Cationic trypsin | PRSS1 | TRP1 | TRY1 | TRY1_BOVIN | TRYP1 | Trypsin | Trypsin I |
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| Type: | Enzyme |
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| Mol. Mass.: | 25790.52 |
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| Organism: | Bos taurus (bovine) |
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| Description: | P00760 |
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| Residue: | 246 |
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| Sequence: | MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVS
AAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLN
SRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQIT
SNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIK
QTIASN
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| BDBM50112487 |
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| n/a |
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| Name | BDBM50112487 |
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| Synonyms: | 3-{3-[4-(1-Acetyl-piperidin-4-yloxy)-3-trifluoromethyl-phenylamino]-propenyl}-4-hydroxy-benzamidine | CHEMBL26400 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H27F3N4O3 |
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| Mol. Mass. | 476.4914 |
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| SMILES | CC(=O)N1CCC(CC1)Oc1ccc(NC\C=C\c2cc(ccc2O)C(N)=N)cc1C(F)(F)F |
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| Structure | 
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