| Reaction Details |
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 | Report a problem with these data |
| Target | Serine protease 1 |
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| Ligand | BDBM50112496 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_212328 |
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| Ki | 870±n/a nM |
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| Citation |  Wu, S; Guilford, WJ; Chou, YL; Griedel, BD; Liang, A; Sakata, S; Shaw, KJ; Trinh, L; Xu, W; Zhao, Z; Morrissey, MM Design and synthesis of aminophenol-based factor Xa inhibitors. Bioorg Med Chem Lett12:1307-10 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine protease 1 |
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| Name: | Serine protease 1 |
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| Synonyms: | Beta-Trypsin | Cationic trypsin | PRSS1 | TRP1 | TRY1 | TRY1_BOVIN | TRYP1 | Trypsin | Trypsin I |
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| Type: | Enzyme |
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| Mol. Mass.: | 25790.52 |
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| Organism: | Bos taurus (bovine) |
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| Description: | P00760 |
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| Residue: | 246 |
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| Sequence: | MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVS
AAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLN
SRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQIT
SNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIK
QTIASN
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| BDBM50112496 |
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| n/a |
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| Name | BDBM50112496 |
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| Synonyms: | CHEMBL26709 | N-[3-(5-Carbamimidoyl-2-hydroxy-phenyl)-allyl]-N-[4-(1-carboxymethyl-piperidin-4-yloxy)-3-trifluoromethyl-phenyl]-succinamic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C28H31F3N4O7 |
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| Mol. Mass. | 592.5635 |
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| SMILES | NC(=N)c1ccc(O)c(\C=C\CN(C(=O)CCC(O)=O)c2ccc(OC3CCN(CC(O)=O)CC3)c(c2)C(F)(F)F)c1 |
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| Structure | 
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