Reaction Details |
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Target | Alpha-synuclein |
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Ligand | BDBM50187665 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_2045852 (CHEMBL4700551) |
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IC50 | 10600±n/a nM |
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Citation | Oliveri, V Toward the discovery and development of effective modulators of ?-synuclein amyloid aggregation. Eur J Med Chem167:10-36 (2019) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Alpha-synuclein |
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Name: | Alpha-synuclein |
Synonyms: | NACP | PARK1 | SNCA | SYUA_HUMAN |
Type: | Protein |
Mol. Mass.: | 14451.42 |
Organism: | Homo sapiens (Human) |
Description: | P37840 |
Residue: | 140 |
Sequence: | MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTK
EQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDP
DNEAYEMPSEEGYQDYEPEA
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BDBM50187665 |
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n/a |
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Name | BDBM50187665 |
Synonyms: | (-)-epigallocatechin | CHEMBL47386 |
Type | Small organic molecule |
Emp. Form. | C15H14O7 |
Mol. Mass. | 306.2675 |
SMILES | O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c1cc(O)c(O)c(O)c1 |r| |
Structure |
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