| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-synuclein |
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| Ligand | BDBM50088360 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2045852 (CHEMBL4700551) |
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| IC50 | 12900±n/a nM |
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| Citation |  Oliveri, V Toward the discovery and development of effective modulators of ?-synuclein amyloid aggregation. Eur J Med Chem167:10-36 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Alpha-synuclein |
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| Name: | Alpha-synuclein |
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| Synonyms: | NACP | PARK1 | SNCA | SYUA_HUMAN |
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| Type: | Protein |
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| Mol. Mass.: | 14451.42 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P37840 |
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| Residue: | 140 |
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| Sequence: | MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTK
EQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDP
DNEAYEMPSEEGYQDYEPEA
|
|
|
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| BDBM50088360 |
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| n/a |
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| Name | BDBM50088360 |
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| Synonyms: | 2,3,4,6-tetrahydroxy-5H-benzo[7]annulen-5-one | 2,3,4,6-tetrahydroxy-5H-benzocycloheptene-5-one | 2,3,4,6-tetrahydroxybenzocyclohepten-5-one | CHEMBL66953 | Hit compound, 2 | Purpurogallin | purpurogalline |
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| Type | Small organic molecule |
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| Emp. Form. | C11H8O5 |
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| Mol. Mass. | 220.1782 |
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| SMILES | Oc1cc2cccc(O)c(=O)c2c(O)c1O |
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| Structure | 
|
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