| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-synuclein |
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| Ligand | BDBM23417 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2045853 (CHEMBL4700552) |
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| IC50 | 800±n/a nM |
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| Citation |  Oliveri, V Toward the discovery and development of effective modulators of ?-synuclein amyloid aggregation. Eur J Med Chem167:10-36 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Alpha-synuclein |
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| Name: | Alpha-synuclein |
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| Synonyms: | NACP | PARK1 | SNCA | SYUA_HUMAN |
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| Type: | Protein |
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| Mol. Mass.: | 14451.42 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P37840 |
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| Residue: | 140 |
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| Sequence: | MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTK
EQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDP
DNEAYEMPSEEGYQDYEPEA
|
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|
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| BDBM23417 |
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| n/a |
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| Name | BDBM23417 |
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| Synonyms: | α-CA inhibitor, 4 | (-)-Epicatechin | (2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol | Epicatechin | L-Epicatechin | cid_72276 |
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| Type | Flavonol |
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| Emp. Form. | C15H14O6 |
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| Mol. Mass. | 290.2681 |
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| SMILES | O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c1ccc(O)c(O)c1 |r| |
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| Structure | 
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