Reaction Details | |||
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Target | Cyclin-T1/Cyclin-dependent kinase 9 | ||
Ligand | BDBM50553495 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_2046740 (CHEMBL4701439) | ||
IC50 | <0.500000±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Cyclin-T1/Cyclin-dependent kinase 9 | |||
Name: | Cyclin-T1/Cyclin-dependent kinase 9 | ||
Synonyms: | CDK9/ Cyclin-T1 | CDK9/CycT1 | CDK9/Cyclin T | CDK9/Cyclin T1 | Cyclin T1/dependent kinase 9 | Cyclin-Dependent Kinase 9 (CDK9) | ||
Type: | Protein Complex | ||
Mol. Mass.: | n/a | ||
Description: | n/a | ||
Components: | This complex has 2 components. | ||
Component 1 | |||
Name: | Cyclin-T1 | ||
Synonyms: | CCNT1 | CCNT1_HUMAN | CycT | CycT1 | Cyclin T | Cyclin T1 | Cyclin-T | ||
Type: | Enzyme Subunit | ||
Mol. Mass.: | 80712.40 | ||
Organism: | Homo sapiens (Human) | ||
Description: | n/a | ||
Residue: | 726 | ||
Sequence: |
| ||
Component 2 | |||
Name: | Cyclin-dependent kinase 9 | ||
Synonyms: | C-2K | CDC2L4 | CDK9 | CDK9_HUMAN | Cell division cycle 2-like protein kinase 4 | Cell division protein kinase 9 | Cyclin-Dependent Kinase 9 (CDK9) | Cyclin-dependent kinase 9 (CDK9) | Serine/threonine-protein kinase PITALRE | TAK | Tat-associated kinase complex catalytic subunit | ||
Type: | Enzyme Subunit | ||
Mol. Mass.: | 42789.13 | ||
Organism: | Homo sapiens (Human) | ||
Description: | n/a | ||
Residue: | 372 | ||
Sequence: |
| ||
BDBM50553495 | |||
n/a | |||
Name | BDBM50553495 | ||
Synonyms: | CHEMBL4786559 | ||
Type | Small organic molecule | ||
Emp. Form. | C27H37ClN6O2 | ||
Mol. Mass. | 513.075 | ||
SMILES | COC[C@H](C)N[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1cccc(NCC2(CCOCC2)C#N)n1 |r,wU:9.12,wD:6.5,3.3,(4.26,-18.37,;5.59,-17.61,;6.92,-18.38,;8.26,-17.62,;8.26,-16.08,;9.59,-18.39,;10.93,-17.63,;12.26,-18.4,;13.6,-17.63,;13.59,-16.1,;12.26,-15.32,;10.93,-16.09,;14.93,-15.33,;16.26,-16.1,;17.59,-15.33,;18.93,-16.09,;18.93,-17.64,;20.27,-18.41,;17.59,-18.42,;16.26,-17.65,;20.25,-15.32,;20.24,-13.79,;21.57,-13.01,;22.91,-13.77,;22.92,-15.32,;24.25,-16.08,;25.59,-15.31,;26.92,-16.07,;25.58,-16.83,;25.57,-18.36,;26.9,-19.14,;28.24,-18.38,;28.25,-16.84,;28.25,-15.3,;29.58,-14.52,;21.59,-16.09,)| | ||
Structure | ![]() |