Reaction Details |
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Target | Macrophage migration inhibitory factor |
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Ligand | BDBM50096003 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_2047513 (CHEMBL4702212) |
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Ki | 1170±n/a nM |
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Citation | Xiao, Z; Chen, D; Song, S; van der Vlag, R; van der Wouden, PE; van Merkerk, R; Cool, RH; Hirsch, AKH; Melgert, BN; Quax, WJ; Poelarends, GJ; Dekker, FJ 7-Hydroxycoumarins Are Affinity-Based Fluorescent Probes for Competitive Binding Studies of Macrophage Migration Inhibitory Factor. J Med Chem63:11920-11933 (2020) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Macrophage migration inhibitory factor |
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Name: | Macrophage migration inhibitory factor |
Synonyms: | GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase |
Type: | Enzyme |
Mol. Mass.: | 12478.18 |
Organism: | Homo sapiens (Human) |
Description: | P14174 |
Residue: | 115 |
Sequence: | MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALC
SLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
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BDBM50096003 |
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n/a |
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Name | BDBM50096003 |
Synonyms: | 7-Hydroxy-3-phenyl-chromen-2-one | 7-hydroxy-3-phenyl-2H-chromen-2-one | CHEMBL153505 | cid_5393176 |
Type | Small organic molecule |
Emp. Form. | C15H10O3 |
Mol. Mass. | 238.2381 |
SMILES | Oc1ccc2cc(-c3ccccc3)c(=O)oc2c1 |
Structure |
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