| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50555497 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2052365 (CHEMBL4707366) |
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| Ki | <1000±n/a nM |
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| Citation |  Sniecikowska, J; Gluch-Lutwin, M; Bucki, A; Wi?ckowska, A; Siwek, A; Jastrzebska-Wiesek, M; Partyka, A; Wilczy?ska, D; Pytka, K; Pociecha, K; Cios, A; Wyska, E; Weso?owska, A; Paw?owski, M; Varney, MA; Newman-Tancredi, A; Kolaczkowski, M Novel Aryloxyethyl Derivatives of 1-(1-Benzoylpiperidin-4-yl)methanamine as the Extracellular Regulated Kinases 1/2 (ERK1/2) Phosphorylation-Preferring Serotonin 5-HT J Med Chem62:2750-2771 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 |
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| Type: | Cell-surface receptors |
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| Mol. Mass.: | 50647.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14416 |
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| Residue: | 443 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
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| BDBM50555497 |
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| n/a |
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| Name | BDBM50555497 |
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| Synonyms: | CHEMBL4753988 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H21ClF2N4O2 |
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| Mol. Mass. | 410.845 |
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| SMILES | Fc1ccc(cc1Cl)C(=O)N1CCC(F)(CNCCOc2ccnnc2)CC1 |
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| Structure | 
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