| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2a |
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| Ligand | BDBM50555720 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2053442 (CHEMBL4708443) |
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| Ki | 28±n/a nM |
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| Citation |  Ceni, C; Catarzi, D; Varano, F; Ben, DD; Marucci, G; Buccioni, M; Volpini, R; Angeli, A; Nocentini, A; Gratteri, P; Supuran, CT; Colotta, V Discovery of first-in-class multi-target adenosine A Eur J Med Chem201:0 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2a |
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| Name: | Adenosine receptor A2a |
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| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44716.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P29274 |
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| Residue: | 412 |
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| Sequence: | MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
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| BDBM50555720 |
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| n/a |
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| Name | BDBM50555720 |
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| Synonyms: | CHEMBL4764804 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H21N7O3S |
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| Mol. Mass. | 487.534 |
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| SMILES | Nc1nc(cn2c1nn(-c1ccccc1)c2=O)-c1ccc(NCc2ccc(cc2)S(N)(=O)=O)cc1 |
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| Structure | 
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