| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Aryl hydrocarbon receptor |
|---|
| Ligand | BDBM50525572 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2056211 (CHEMBL4711212) |
|---|
| IC50 | 2430±n/a nM |
|---|
| Citation |  Goya-Jorge, E; Rampal, C; Loones, N; Barigye, SJ; Carpio, LE; Gozalbes, R; Ferroud, C; Sylla-Iyarreta Veitía, M; Giner, RM Targeting the aryl hydrocarbon receptor with a novel set of triarylmethanes. Eur J Med Chem207:0 (2020) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Aryl hydrocarbon receptor |
|---|
| Name: | Aryl hydrocarbon receptor |
|---|
| Synonyms: | AHR | AHR_HUMAN | BHLHE76 | Class E basic helix-loop-helix protein 76 | aryl hydrocarbon receptor precursor |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 96143.77 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1503828 |
|---|
| Residue: | 848 |
|---|
| Sequence: | MNSSSANITYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDV
INKLDKLSVLRLSVSYLRAKSFFDVALKSSPTERNGGQDNCRAANFREGLNLQEGEFLLQ
ALNGFVLVVTTDALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNP
SQCTESGQGIEEATGLPQTVVCYNPDQIPPENSPLMERCFICRLRCLLDNSSGFLAMNFQ
GKLKYLHGQKKKGKDGSILPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPIGC
DAKGRIVLGYTEAELCTRGSGYQFIHAADMLYCAESHIRMIKTGESGMIVFRLLTKNNRW
TWVQSNARLLYKNGRPDYIIVTQRPLTDEEGTEHLRKRNTKLPFMFTTGEAVLYEATNPF
PAIMDPLPLRTKNGTSGKDSATTSTLSKDSLNPSSLLAAMMQQDESIYLYPASSTSSTAP
FENNFFNESMNECRNWQDNTAPMGNDTILKHEQIDQPQDVNSFAGGHPGLFQDSKNSDLY
SIMKNLGIDFEDIRHMQNEKFFRNDFSGEVDFRDIDLTDEILTYVQDSLSKSPFIPSDYQ
QQQSLALNSSCMVQEHLHLEQQQQHHQKQVVVEPQQQLCQKMKHMQVNGMFENWNSNQFV
PFNCPQQDPQQYNVFTDLHGISQEFPYKSEMDSMPYTQNFISCNQPVLPQHSKCTELDYP
MGSFEPSPYPTTSSLEDFVTCLQLPENQKHGLNPQSAIITPQTCYAGAVSMYQCQPEPQH
THVGQMQYNPVLPGQQAFLNKFQNGVLNETYPAELNNINNTQTTTHLQPLHHPSEARPFP
DLTSSGFL
|
|
|
|---|
| BDBM50525572 |
|---|
| n/a |
|---|
| Name | BDBM50525572 |
|---|
| Synonyms: | CH-223191 | CHEMBL1743245 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H19N5O |
|---|
| Mol. Mass. | 333.3871 |
|---|
| SMILES | Cc1ccccc1\N=N\c1ccc(NC(=O)c2ccnn2C)c(C)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
