| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50558230 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2062336 (CHEMBL4717589) |
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| Ki | 4.1±n/a nM |
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| Citation |  Arena, E; Cacciatore, I; Cerasa, LS; Turkez, H; Pittalą, V; Pasquinucci, L; Marrazzo, A; Parenti, C; Di Stefano, A; Prezzavento, O New bifunctional antioxidant/?1 agonist ligands: Preliminary chemico-physical and biological evaluation. Bioorg Med Chem24:3149-56 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
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| Type: | Protein |
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| Mol. Mass.: | 25307.17 |
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| Organism: | Cavia porcellus (Guinea pig) |
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| Description: | Q60492 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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| BDBM50558230 |
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| n/a |
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| Name | BDBM50558230 |
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| Synonyms: | CHEMBL4749030 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H28FNO2S2 |
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| Mol. Mass. | 397.57 |
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| SMILES | Fc1ccc(CN2CCC(CC2)OC(=O)CCCCC2CCSS2)cc1 |
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| Structure | 
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