| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-galactoside alpha-2,6-sialyltransferase 1 |
|---|
| Ligand | BDBM50559955 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2070766 (CHEMBL4726300) |
|---|
| Ki | 29±n/a nM |
|---|
| Citation |  Montgomery, AP; Dobie, C; Szabo, R; Hallam, L; Ranson, M; Yu, H; Skropeta, D Design, synthesis and evaluation of carbamate-linked uridyl-based inhibitors of human ST6Gal I. Bioorg Med Chem28:0 (2020) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Beta-galactoside alpha-2,6-sialyltransferase 1 |
|---|
| Name: | Beta-galactoside alpha-2,6-sialyltransferase 1 |
|---|
| Synonyms: | 2.4.99.1 | Alpha 2,6-ST 1 | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1 | SIAT1_RAT | ST6Gal I | ST6GalI | Sialyltransferase 1 | Siat1 | St6gal1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 46766.92 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_12371 |
|---|
| Residue: | 403 |
|---|
| Sequence: | MIHTNLKKKFSLFILVFLLFAVICVWKKGSDYEALTLQAKEFQMPKSQEKVAMGSASQVV
FSNSKQDPKEDIPILSYHRVTAKVKPQPSFQVWDKDSTYSKLNPRLLKIWRNYLNMNKYK
VSYKGPGPGVKFSVEALRCHLRDHVNVSMIEATDFPFNTTEWEGYLPKENFRTKVGPWQR
CAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPTDNFQQDVGSKTTIRLMNSQLVTTEKRF
LKDSLYTEGILIVWDPSVYHADIPKWYQKPDYNFFETYKSYRRLNPSQPFYILKPQMPWE
LWDIIQEISADLIQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSKRKTDVCYYHQKFFDSA
CTMGAYHPLLFEKNMVKHLNEGTDEDIYLFGKATLSGFRNIRC
|
|
|
|---|
| BDBM50559955 |
|---|
| n/a |
|---|
| Name | BDBM50559955 |
|---|
| Synonyms: | CHEMBL4776007 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H27N4Na3O15P2 |
|---|
| Mol. Mass. | 730.3951 |
|---|
| SMILES | [Na;v0+].[Na;v0+].[Na;v0+].[#6]-[#6](=O)-[#7]-[#6@@H]-1-[#6@@H](-[#8])-[#6]=[#6](-[#8]-[#6@@H]-1-[#8]-c1ccccc1)-[#6@@H](-[#8]P([#8-])(=O)[#8]-[#6]-[#6@H]-1-[#8]-[#6@H](-[#6@H](-[#8])-[#6@@H]-1-[#8])-n1ccc(-[#7])nc1=O)P([#8-])([#8-])=O |r,c:7| |
|---|
| Structure | 
|
|---|
Search and Browse
