| Reaction Details |
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 | Report a problem with these data |
| Target | Arginase-1 |
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| Ligand | BDBM50350311 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2074192 (CHEMBL4729726) |
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| IC50 | 800±n/a nM |
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| Citation |  Borek, B; Gajda, T; Golebiowski, A; Blaszczyk, R Boronic acid-based arginase inhibitors in cancer immunotherapy. Bioorg Med Chem28:0 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Arginase-1 |
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| Name: | Arginase-1 |
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| Synonyms: | ARGI1_RAT | Arg1 | Liver-type arginase | Type I arginase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 34976.26 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_108287 |
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| Residue: | 323 |
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| Sequence: | MSSKPKPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPN
DSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCV
IWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLR
DVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVF
TPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALT
LSCFGTKREGNHKPETDYLKPPK
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| BDBM50350311 |
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| n/a |
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| Name | BDBM50350311 |
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| Synonyms: | CHEMBL1812661 |
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| Type | Small organic molecule |
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| Emp. Form. | C6H14BNO4 |
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| Mol. Mass. | 174.991 |
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| SMILES | [NH3+][C@@H](CCCCB(O)O)C([O-])=O |r| |
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| Structure | 
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