| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Arginase-2, mitochondrial |
|---|
| Ligand | BDBM50561053 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2074199 (CHEMBL4729733) |
|---|
| IC50 | 500±n/a nM |
|---|
| Citation |  Borek, B; Gajda, T; Golebiowski, A; Blaszczyk, R Boronic acid-based arginase inhibitors in cancer immunotherapy. Bioorg Med Chem28:0 (2020) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Arginase-2, mitochondrial |
|---|
| Name: | Arginase-2, mitochondrial |
|---|
| Synonyms: | ARG2 | ARGI2_HUMAN | Arginase II | Kidney-type arginase | Non-hepatic arginase | Type II arginase |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 38576.93 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_978892 |
|---|
| Residue: | 354 |
|---|
| Sequence: | MSLRGSLSRLLQTRVHSILKKSVHSVAVIGAPFSQGQKRKGVEHGPAAIREAGLMKRLSS
LGCHLKDFGDLSFTPVPKDDLYNNLIVNPRSVGLANQELAEVVSRAVSDGYSCVTLGGDH
SLAIGTISGHARHCPDLCVVWVDAHADINTPLTTSSGNLHGQPVSFLLRELQDKVPQLPG
FSWIKPCISSASIVYIGLRDVDPPEHFILKNYDIQYFSMRDIDRLGIQKVMERTFDLLIG
KRQRPIHLSFDIDAFDPTLAPATGTPVVGGLTYREGMYIAEEIHNTGLLSALDLVEVNPQ
LATSEEEAKTTANLAVDVIASSFGQTREGGHIVYDQLPTPSSPDESENQARVRI
|
|
|
|---|
| BDBM50561053 |
|---|
| n/a |
|---|
| Name | BDBM50561053 |
|---|
| Synonyms: | CHEMBL4750602 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H26BN5O5 |
|---|
| Mol. Mass. | 367.208 |
|---|
| SMILES | C[C@@H]1N(C[C@@H](CCB(O)O)C[C@]1(N)C(O)=O)C(=O)[C@@H](N)Cc1c[nH]cn1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
