| Reaction Details |
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 | Report a problem with these data |
| Target | Coagulation factor VII |
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| Ligand | BDBM50124010 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_48466 (CHEMBL663029) |
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| IC50 | >100000±n/a nM |
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| Citation |  Inoue, J; Nakamura, M; Cui, YS; Sakai, Y; Sakai, O; Hill, JR; Wang, KK; Yuen, PW Structure-activity relationship study and drug profile of N-(4-fluorophenylsulfonyl)-L-valyl-L-leucinal (SJA6017) as a potent calpain inhibitor. J Med Chem46:868-71 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Coagulation factor VII |
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| Name: | Coagulation factor VII |
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| Synonyms: | Eptacog alfa | F7 | FA7_HUMAN | Factor VIIa | Factor VIIa (fVIIa) | Proconvertin | SPCA | Thrombin and coagulation factor VII | serum prothrombin conversion accelerator |
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| Type: | Enzyme |
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| Mol. Mass.: | 51599.89 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 466 |
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| Sequence: | MVSQALRLLCLLLGLQGCLAAGGVAKASGGETRDMPWKPGPHRVFVTQEEAHGVLHRRRR
ANAFLEELRPGSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGS
CKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSL
LADGVSCTPTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQLCGG
TLINTIWVVSAAHCFDKIKNWRNLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTN
HDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVL
NVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTG
IVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRPGVLLRAPFP
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| BDBM50124010 |
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| n/a |
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| Name | BDBM50124010 |
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| Synonyms: | 2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-methyl-butyl)-3-methyl-butyramide | CHEMBL168471 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H25FN2O4S |
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| Mol. Mass. | 372.455 |
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| SMILES | CC(C)C[C@@H](NC(=O)[C@@H](NS(=O)(=O)c1ccc(F)cc1)C(C)C)C=O |
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| Structure | 
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