| Reaction Details |
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 | Report a problem with these data |
| Target | N-formyl peptide receptor 2 |
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| Ligand | BDBM350546 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2081556 (CHEMBL4737347) |
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| EC50 | 0.880000±n/a nM |
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| Citation |  Maciuszek, M; Ortega-Gomez, A; Maas, SL; Perretti, M; Merritt, A; Soehnlein, O; Chapman, TM Synthesis and evaluation of novel cyclopentane urea FPR2 agonists and their potential application in the treatment of cardiovascular inflammation. Eur J Med Chem214:0 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| N-formyl peptide receptor 2 |
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| Name: | N-formyl peptide receptor 2 |
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| Synonyms: | ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 38968.35 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P25090 |
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| Residue: | 351 |
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| Sequence: | METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVT
TICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIA
LDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNF
ASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPL
RVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPM
LYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
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| BDBM350546 |
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| n/a |
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| Name | BDBM350546 |
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| Synonyms: | US10208071, Compound 8 | US10434112, Compound 90 | US10799518, Compound 8 | {[(2S)-2-{[(4- bromophenyl)carbamoyl]amino}-4- methylpentanoyl]amino}acetic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C15H20BrN3O4 |
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| Mol. Mass. | 386.241 |
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| SMILES | CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)NCC(O)=O |r| |
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| Structure | 
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