| Reaction Details |
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 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] A |
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| Ligand | BDBM50564115 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2086574 (CHEMBL4767837) |
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| IC50 | >50000±n/a nM |
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| Citation |  Herrera-Arozamena, C; Estrada-Valencia, M; Pérez, C; Lagartera, L; Morales-García, JA; Pérez-Castillo, A; Franco-Gonzalez, JF; Michalska, P; Duarte, P; León, R; López, MG; Mills, A; Gago, F; García-Yagüe, ÁJ; Fernández-Ginés, R; Cuadrado, A; Rodríguez-Franco, MI Tuning melatonin receptor subtype selectivity in oxadiazolone-based analogues: Discovery of QR2 ligands and NRF2 activators with neurogenic properties. Eur J Med Chem190:0 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Amine oxidase [flavin-containing] A |
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| Name: | Amine oxidase [flavin-containing] A |
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| Synonyms: | AOFA_HUMAN | Amine oxidase (flavin-containing) A | MAO-A | MAOA | Monoamine oxidase | Monoamine oxidase type A | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAOA) |
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| Type: | Protein |
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| Mol. Mass.: | 59689.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21397 |
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| Residue: | 527 |
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| Sequence: | MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHV
DYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIA
YLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNI
NVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKL
NHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPM
GAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADR
LAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYG
RVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKD
VPAVEITHTFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKLLPRS
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| BDBM50564115 |
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| n/a |
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| Name | BDBM50564115 |
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| Synonyms: | CHEMBL4794879 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H16N4O2 |
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| Mol. Mass. | 272.3024 |
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| SMILES | CNc1nnc(CCc2c[nH]c3ccc(OC)cc23)o1 |
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| Structure | 
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