| Reaction Details |
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 | Report a problem with these data |
| Target | M-phase inducer phosphatase 2 |
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| Ligand | BDBM50129584 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_49025 (CHEMBL662064) |
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| IC50 | 4200±n/a nM |
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| Citation |  Sohn, J; Kiburz, B; Li, Z; Deng, L; Safi, A; Pirrung, MC; Rudolph, J Inhibition of Cdc25 phosphatases by indolyldihydroxyquinones. J Med Chem46:2580-8 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| M-phase inducer phosphatase 2 |
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| Name: | M-phase inducer phosphatase 2 |
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| Synonyms: | CDC25B | CDC25HU2 | Dual specificity phosphatase (CDC25B) | Dual specificity phosphatase Cdc25B | M-phase inducer phosphatase 2 (CDC25B) | MPIP2_HUMAN |
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| Type: | Protein |
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| Mol. Mass.: | 64985.27 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 580 |
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| Sequence: | MEVPQPEPAPGSALSPAGVCGGAQRPGHLPGLLLGSHGLLGSPVRAAASSPVTTLTQTMH
DLAGLGSETPKSQVGTLLFRSRSRLTHLSLSRRASESSLSSESSESSDAGLCMDSPSPMD
PHMAEQTFEQAIQAASRIIRNEQFAIRRFQSMPVRLLGHSPVLRNITNSQAPDGRRKSEA
GSGAASSSGEDKENDGFVFKMPWKPTHPSSTHALAEWASRREAFAQRPSSAPDLMCLSPD
RKMEVEELSPLALGRFSLTPAEGDTEEDDGFVDILESDLKDDDAVPPGMESLISAPLVKT
LEKEEEKDLVMYSKCQRLFRSPSMPCSVIRPILKRLERPQDRDTPVQNKRRRSVTPPEEQ
QEAEEPKARVLRSKSLCHDEIENLLDSDHRELIGDYSKAFLLQTVDGKHQDLKYISPETM
VALLTGKFSNIVDKFVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPIAPCSLDKR
VILIFHCEFSSERGPRMCRFIRERDRAVNDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQ
DYRPMNHEAFKDELKTFRLKTRSWAGERSRRELCSRLQDQ
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| BDBM50129584 |
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| n/a |
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| Name | BDBM50129584 |
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| Synonyms: | 3-(7-Benzyloxy-1H-indol-3-yl)-2,5-dihydroxy-[1,4]benzoquinone | CHEMBL84910 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H15NO5 |
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| Mol. Mass. | 361.3475 |
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| SMILES | O=C1CC(=O)C(=O)C(c2c[nH]c3c(OCc4ccccc4)cccc23)C1=O |
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| Structure | 
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