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TargetProtein ADM2
LigandBDBM50570386
Substrate/Competitorn/a
Meas. Tech.ChEMBL_2112107 (CHEMBL4820957)
IC50 1259±n/a nM
Citation Zirimwabagabo, JOJailani, ABAAvgoustou, PTozer, MJGibson, KRGlossop, PAMills, JEJPorter, RABlaney, PWang, NSkerry, TMRichards, GOHarrity, JPA Discovery of a First-In-Class Small Molecule Antagonist against the Adrenomedullin-2 Receptor: Structure-Activity Relationships and Optimization. J Med Chem64:3299-3319 (2021) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Protein ADM2
Name:Protein ADM2
Synonyms:ADM2 | ADM2_HUMAN | AM2
Type:PROTEIN
Mol. Mass.:15883.28
Organism:Homo sapiens (Human)
Description:ChEMBL_556927
Residue:148
Sequence:
MARIPTAALGCISLLCLQLPGSLSRSLGGDPRPVKPREPPARSPSSSLQPRHPAPRPVVW
KLHRALQAQRGAGLAPVMGQPLRDGGRQHSGPRRHSGPRRTQAQLLRVGCVLGTCQVQNL
SHRLWQLMGPAGRQDSAPVDPSSPHSYG
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BDBM50570386
n/a
NameBDBM50570386
Synonyms:CHEMBL4864804
TypeSmall organic molecule
Emp. Form.C26H30N4O4
Mol. Mass.462.5408
SMILESCN1C(=O)NC(=O)C11Cc2ccc(NC(=O)CN(Cc3ccccc3)C(=O)C(C)(C)C)cc2C1
Structure
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