Reaction Details |
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Target | Interleukin-15 |
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Ligand | BDBM50571049 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_2113696 (CHEMBL4822546) |
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IC50 | 16400±n/a nM |
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Citation | Smadja, J; Quéméner, A; Maillasson, M; Sicard, B; Leray, A; Arzel, L; Lebreton, J; Mortier, E; Dubreuil, D; Mathé-Allainmat, M Rational modification, synthesis and biological evaluation of N-substituted phthalazinone derivatives designed to target interleukine-15 protein. Bioorg Med Chem39:0 (2021) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Interleukin-15 |
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Name: | Interleukin-15 |
Synonyms: | IL-15 | IL15_MOUSE | Il15 | Interleukin-15 |
Type: | PROTEIN |
Mol. Mass.: | 18588.73 |
Organism: | Mus musculus |
Description: | ChEMBL_120403 |
Residue: | 162 |
Sequence: | MKILKPYMRNTSISCYLCFLLNSHFLTEAGIHVFILGCVSVGLPKTEANWIDVRYDLEKI
ESLIQSIHIDTTLYTDSDFHPSCKVTAMNCFLLELQVILHEYSNMTLNETVRNVLYLANS
TLSSNKNVAESGCKECEELEEKTFTEFLQSFIRIVQMFINTS
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BDBM50571049 |
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n/a |
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Name | BDBM50571049 |
Synonyms: | CHEMBL4868024 |
Type | Small organic molecule |
Emp. Form. | C33H42Cl2N6O4S |
Mol. Mass. | 689.695 |
SMILES | CCOC(CCn1c(Cc2nn(C)c(=O)c3ccccc23)nnc1SCCCCCCCC(=O)Nc1ccc(Cl)cc1Cl)OCC |
Structure |
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