Reaction Details |
| Report a problem with these data |
Target | Interleukin-15 |
---|
Ligand | BDBM50571057 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEMBL_2113696 (CHEMBL4822546) |
---|
IC50 | 11700±n/a nM |
---|
Citation | Smadja, J; Quéméner, A; Maillasson, M; Sicard, B; Leray, A; Arzel, L; Lebreton, J; Mortier, E; Dubreuil, D; Mathé-Allainmat, M Rational modification, synthesis and biological evaluation of N-substituted phthalazinone derivatives designed to target interleukine-15 protein. Bioorg Med Chem39:0 (2021) [PubMed] Article |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Interleukin-15 |
---|
Name: | Interleukin-15 |
Synonyms: | IL-15 | IL15_MOUSE | Il15 | Interleukin-15 |
Type: | PROTEIN |
Mol. Mass.: | 18588.73 |
Organism: | Mus musculus |
Description: | ChEMBL_120403 |
Residue: | 162 |
Sequence: | MKILKPYMRNTSISCYLCFLLNSHFLTEAGIHVFILGCVSVGLPKTEANWIDVRYDLEKI
ESLIQSIHIDTTLYTDSDFHPSCKVTAMNCFLLELQVILHEYSNMTLNETVRNVLYLANS
TLSSNKNVAESGCKECEELEEKTFTEFLQSFIRIVQMFINTS
|
|
|
BDBM50571057 |
---|
n/a |
---|
Name | BDBM50571057 |
Synonyms: | CHEMBL4847472 |
Type | Small organic molecule |
Emp. Form. | C29H32Cl2N6O3S |
Mol. Mass. | 615.574 |
SMILES | Cn1c(Cc2nn(CCC=O)c(=O)c3ccccc23)nnc1SCCCCCCCC(=O)Nc1ccc(Cl)cc1Cl |
Structure |
|