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TargetInterleukin-2
LigandBDBM50571041
Substrate/Competitorn/a
Meas. Tech.ChEMBL_2113698 (CHEMBL4822548)
IC50 8600±n/a nM
Citation Smadja, JQuéméner, AMaillasson, MSicard, BLeray, AArzel, LLebreton, JMortier, EDubreuil, DMathé-Allainmat, M Rational modification, synthesis and biological evaluation of N-substituted phthalazinone derivatives designed to target interleukine-15 protein. Bioorg Med Chem39:0 (2021) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Interleukin-2
Name:Interleukin-2
Synonyms:IL-2 | IL2 | IL2_HUMAN | INN=Aldesleukin | Interleukin-2 | Interleukin-2 (IL-2) | T-cell growth factor | TCGF
Type:Enzyme
Mol. Mass.:17630.05
Organism:Homo sapiens (Human)
Description:P60568
Residue:153
Sequence:
MYRMQLLSCIALSLALVTNSAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRML
TFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSE
TTFMCEYADETATIVEFLNRWITFCQSIISTLT
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BDBM50571041
n/a
NameBDBM50571041
Synonyms:CHEMBL4864820
TypeSmall organic molecule
Emp. Form.C23H20Cl2N6O3S
Mol. Mass.531.414
SMILESCn1nc(Cc2nnc(SCC(=O)Nc3ccc(Cl)cc3Cl)n2CCC=O)c2ccccc2c1=O
Structure
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