Reaction Details |
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Target | Mu-type opioid receptor |
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Ligand | BDBM50137998 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_145149 (CHEMBL755953) |
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Ki | 4.4±n/a nM |
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Citation | Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL 10-Ketomorphinan and 3-substituted-3-desoxymorphinan analogues as mixed kappa and micro opioid ligands: synthesis and biological evaluation of their binding affinity at opioid receptors. J Med Chem47:165-74 (2003) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Mu-type opioid receptor |
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Name: | Mu-type opioid receptor |
Synonyms: | M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 11165.58 |
Organism: | GUINEA PIG |
Description: | P97266 |
Residue: | 98 |
Sequence: | YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSI
FTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
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BDBM50137998 |
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n/a |
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Name | BDBM50137998 |
Synonyms: | 3-Benzylamino-10-keto-N-cyclobutylmethylmorphinan | CHEMBL49106 |
Type | Small organic molecule |
Emp. Form. | C28H32N2O2 |
Mol. Mass. | 428.5659 |
SMILES | O=C(Nc1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3CCC3)c2c1)c1ccccc1 |
Structure |
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