| Reaction Details |
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 | Report a problem with these data |
| Target | Cyclin-C |
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| Ligand | BDBM50573479 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2119597 (CHEMBL4828663) |
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| IC50 | 274±n/a nM |
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| Citation |  Hatcher, JM; Vatsan, PS; Wang, E; Jiang, J; Gray, NS Development of Highly Potent and Selective Pyrazolopyridine Inhibitor of CDK8/19. ACS Med Chem Lett12:1689-1693 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cyclin-C |
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| Name: | Cyclin-C |
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| Synonyms: | CCNC | CCNC_HUMAN | Cyclin C | SRB11 homolog | hSRB11 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 33244.88 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_107900 |
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| Residue: | 283 |
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| Sequence: | MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLSEEEYWKLQIFFTNVIQALGEHLKLRQQ
VIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVLKTRF
SYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDMLLPLAWRIV
NDTYRTDLCLLYPPFMIALACLHVACVVQQKDARQWFAELSVDMEKILEIIRVILKLYEQ
WKNFDERKEMATILSKMPKPKPPPNSEGEQGPNGSQNSSYSQS
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| BDBM50573479 |
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| n/a |
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| Name | BDBM50573479 |
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| Synonyms: | CHEMBL4854223 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H21N7O |
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| Mol. Mass. | 387.4377 |
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| SMILES | O=C1NCCC11CCN(CC1)c1c(cnc2[nH]ccc12)-c1ccc2ncnn2c1 |
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| Structure | 
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