| Reaction Details |
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 | Report a problem with these data |
| Target | Fatty acid 2-hydroxylase |
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| Ligand | BDBM50574654 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2122943 (CHEMBL4832176) |
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| IC50 | >20000±n/a nM |
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| Citation |  Bononi, G; Tonarini, G; Poli, G; Barravecchia, I; Caligiuri, I; Macchia, M; Rizzolio, F; Demontis, GC; Minutolo, F; Granchi, C; Tuccinardi, T Monoacylglycerol lipase (MAGL) inhibitors based on a diphenylsulfide-benzoylpiperidine scaffold. Eur J Med Chem223:0 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Fatty acid 2-hydroxylase |
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| Name: | Fatty acid 2-hydroxylase |
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| Synonyms: | FA2H | FA2H_HUMAN | FAAH | FAXDC1 | Fatty acid alpha-hydroxylase | Fatty acid hydroxylase domain-containing protein 1 |
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| Type: | Protein |
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| Mol. Mass.: | 42806.38 |
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| Organism: | Human |
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| Description: | Q7L5A8 |
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| Residue: | 372 |
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| Sequence: | MAPAPPPAASFSPSEVQRRLAAGACWVRRGARLYDLSSFVRHHPGGEQLLRARAGQDISA
DLDGPPHRHSANARRWLEQYYVGELRGEQQGSMENEPVALEETQKTDPAMEPRFKVVDWD
KDLVDWRKPLLWQVGHLGEKYDEWVHQPVTRPIRLFHSDLIEGLSKTVWYSVPIIWVPLV
LYLSWSYYRTFAQGNVRLFTSFTTEYTVAVPKSMFPGLFMLGTFLWSLIEYLIHRFLFHM
KPPSDSYYLIMLHFVMHGQHHKAPFDGSRLVFPPVPASLVIGVFYLCMQLILPEAVGGTV
FAGGLLGYVLYDMTHYYLHFGSPHKGSYLYSLKAHHVKHHFAHQKSGFGISTKLWDYCFH
TLTPEKPHLKTQ
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| BDBM50574654 |
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| n/a |
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| Name | BDBM50574654 |
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| Synonyms: | CHEMBL4870906 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H21F4NO3S |
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| Mol. Mass. | 503.508 |
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| SMILES | Oc1ccc(F)c(c1)C(=O)N1CCC(CC1)C(=O)c1ccc(Sc2cccc(c2)C(F)(F)F)cc1 |
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| Structure | 
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