Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetInterleukin-2
LigandBDBM50575325
Substrate/Competitorn/a
Meas. Tech.ChEMBL_2124825 (CHEMBL4834058)
Kd 22000±n/a nM
Citation Gironda-Martínez, AGorre, ÉMDPrati, LGosalbes, JFDakhel, SCazzamalli, SSamain, FDonckele, EJNeri, D Identification and Validation of New Interleukin-2 Ligands Using DNA-Encoded Libraries. J Med Chem64:17496-17510 (2021) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Interleukin-2
Name:Interleukin-2
Synonyms:IL-2 | IL2 | IL2_HUMAN | INN=Aldesleukin | Interleukin-2 | Interleukin-2 (IL-2) | T-cell growth factor | TCGF
Type:Enzyme
Mol. Mass.:17630.05
Organism:Homo sapiens (Human)
Description:P60568
Residue:153
Sequence:
MYRMQLLSCIALSLALVTNSAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRML
TFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSE
TTFMCEYADETATIVEFLNRWITFCQSIISTLT
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50575325
n/a
NameBDBM50575325
Synonyms:CHEMBL4867370
TypeSmall organic molecule
Emp. Form.C26H30N4O3
Mol. Mass.446.5414
SMILESCOC(=O)[C@H](Cc1ccc(cc1)C#Cc1ccccc1)NC(=O)C[C@@H]1CCCN(C1)C(N)=N |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: