Reaction Details |
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Target | Interleukin-2 |
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Ligand | BDBM50575325 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_2124825 (CHEMBL4834058) |
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Kd | 22000±n/a nM |
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Citation | Gironda-Martínez, A; Gorre, ÉMD; Prati, L; Gosalbes, JF; Dakhel, S; Cazzamalli, S; Samain, F; Donckele, EJ; Neri, D Identification and Validation of New Interleukin-2 Ligands Using DNA-Encoded Libraries. J Med Chem64:17496-17510 (2021) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Interleukin-2 |
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Name: | Interleukin-2 |
Synonyms: | IL-2 | IL2 | IL2_HUMAN | INN=Aldesleukin | Interleukin-2 | Interleukin-2 (IL-2) | T-cell growth factor | TCGF |
Type: | Enzyme |
Mol. Mass.: | 17630.05 |
Organism: | Homo sapiens (Human) |
Description: | P60568 |
Residue: | 153 |
Sequence: | MYRMQLLSCIALSLALVTNSAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRML
TFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSE
TTFMCEYADETATIVEFLNRWITFCQSIISTLT
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BDBM50575325 |
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n/a |
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Name | BDBM50575325 |
Synonyms: | CHEMBL4867370 |
Type | Small organic molecule |
Emp. Form. | C26H30N4O3 |
Mol. Mass. | 446.5414 |
SMILES | COC(=O)[C@H](Cc1ccc(cc1)C#Cc1ccccc1)NC(=O)C[C@@H]1CCCN(C1)C(N)=N |r| |
Structure |
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