| Reaction Details |
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 | Report a problem with these data |
| Target | Interleukin-2 |
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| Ligand | BDBM387266 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2124827 (CHEMBL4834060) |
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| IC50 | 78±n/a nM |
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| Citation |  Khedkar, NR; Irlapatti, NR; Dadke, D; Kanoje, V; Shaikh, Z; Karche, V; Shinde, V; Deshmukh, G; Patil, A; Jachak, S; Phukan, S; Kizhakinagath, PA; Gholve, M; Bhankhede, T; Daler, J; Nemade, HN; Budhe, S; Pareek, H; Yeshodharan, R; Gupta, R; Kalia, A; Pandey, D; Wagh, A; Kumar, S; Patil, V; Modi, D; Sharma, N; Ahirrao, P; Mehta, M; Kumar, H; Nigade, P; Tamane, K; Mallurwar, S; Kuldharan, S; Pawar, S; Vishwase, G; Bokan, S; Singh, M; Naik, K; Ingawale, S; Shankar, R; Kamalakannan, P; Venugopal, S; George, SK; Padiya, KJ; Nemmani, KVS; Gundu, J; Bhonde, M; Narasimham, L; Sindkhedkar, M; Shah, C; Sinha, N; Sharma, S; Bakhle, D; Kamboj, RK; Palle, VP Discovery of a Novel Potent and Selective Calcium Release-Activated Calcium Channel Inhibitor: 2,6-Difluoro- J Med Chem64:17004-17030 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Interleukin-2 |
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| Name: | Interleukin-2 |
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| Synonyms: | IL-2 | IL2 | IL2_HUMAN | INN=Aldesleukin | Interleukin-2 | Interleukin-2 (IL-2) | T-cell growth factor | TCGF |
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| Type: | Enzyme |
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| Mol. Mass.: | 17630.05 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P60568 |
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| Residue: | 153 |
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| Sequence: | MYRMQLLSCIALSLALVTNSAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRML
TFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSE
TTFMCEYADETATIVEFLNRWITFCQSIISTLT
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| BDBM387266 |
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| n/a |
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| Name | BDBM387266 |
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| Synonyms: | N-(5′- (4-Ethyl-5-oxo-4,5- dihydro-1,3,4- oxadiazol-2-yl)-2′- methyl-[1,1′- biphenyl]-4-yl)-2,6- difluorobenzamide | US10292981, Example 34 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H19F2N3O3 |
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| Mol. Mass. | 435.4228 |
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| SMILES | CCn1nc(oc1=O)-c1ccc(C)c(c1)-c1ccc(NC(=O)c2c(F)cccc2F)cc1 |
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| Structure | 
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