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TargetBifunctional epoxide hydrolase 2
LigandBDBM50143930
Substrate/Competitorn/a
Meas. Tech.ChEMBL_67377 (CHEMBL677487)
IC50 33000±n/a nM
Citation Kim, IHMorisseau, CWatanabe, THammock, BD Design, synthesis, and biological activity of 1,3-disubstituted ureas as potent inhibitors of the soluble epoxide hydrolase of increased water solubility. J Med Chem47:2110-22 (2004) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Bifunctional epoxide hydrolase 2
Name:Bifunctional epoxide hydrolase 2
Synonyms:Eph2 | Ephx2 | Epoxide hydratase | HYES_MOUSE | Soluble epoxide hydrolase (sEH)
Type:Enzyme
Mol. Mass.:62512.06
Organism:Mus musculus (Mouse)
Description:P34914
Residue:554
Sequence:
MALRVAAFDLDGVLALPSIAGAFRRSEEALALPRDFLLGAYQTEFPEGPTEQLMKGKITF
SQWVPLMDESYRKSSKACGANLPENFSISQIFSQAMAARSINRPMLQAAIALKKKGFTTC
IVTNNWLDDGDKRDSLAQMMCELSQHFDFLIESCQVGMIKPEPQIYNFLLDTLKAKPNEV
VFLDDFGSNLKPARDMGMVTILVHNTASALRELEKVTGTQFPEAPLPVPCNPNDVSHGYV
TVKPGIRLHFVEMGSGPALCLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSSSP
PEIEEYAMELLCKEMVTFLDKLGIPQAVFIGHDWAGVMVWNMALFYPERVRAVASLNTPF
MPPDPDVSPMKVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRASDETGFIAVHK
ATEIGGILVNTPEDPNLSKITTEEEIEFYIQQFKKTGFRGPLNWYRNTERNWKWSCKGLG
RKILVPALMVTAEKDIVLRPEMSKNMEKWIPFLKRGHIEDCGHWTQIEKPTEVNQILIKW
LQTEVQNPSVTSKI
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  Blast E-value cutoff:
BDBM50143930
n/a
NameBDBM50143930
Synonyms:(3-Cyclohexyl-ureido)-acetic acid methyl ester | CHEMBL66518 | methyl 2-(3-cyclohexylureido)acetate
TypeSmall organic molecule
Emp. Form.C10H18N2O3
Mol. Mass.214.2615
SMILESCOC(=O)CNC(=O)NC1CCCCC1
Structure
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