| Reaction Details |
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 | Report a problem with these data |
| Target | Bifunctional epoxide hydrolase 2 |
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| Ligand | BDBM50143922 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_67377 (CHEMBL677487) |
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| IC50 | 50±n/a nM |
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| Citation |  Kim, IH; Morisseau, C; Watanabe, T; Hammock, BD Design, synthesis, and biological activity of 1,3-disubstituted ureas as potent inhibitors of the soluble epoxide hydrolase of increased water solubility. J Med Chem47:2110-22 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Bifunctional epoxide hydrolase 2 |
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| Name: | Bifunctional epoxide hydrolase 2 |
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| Synonyms: | Eph2 | Ephx2 | Epoxide hydratase | HYES_MOUSE | Soluble epoxide hydrolase (sEH) |
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| Type: | Enzyme |
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| Mol. Mass.: | 62512.06 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | P34914 |
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| Residue: | 554 |
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| Sequence: | MALRVAAFDLDGVLALPSIAGAFRRSEEALALPRDFLLGAYQTEFPEGPTEQLMKGKITF
SQWVPLMDESYRKSSKACGANLPENFSISQIFSQAMAARSINRPMLQAAIALKKKGFTTC
IVTNNWLDDGDKRDSLAQMMCELSQHFDFLIESCQVGMIKPEPQIYNFLLDTLKAKPNEV
VFLDDFGSNLKPARDMGMVTILVHNTASALRELEKVTGTQFPEAPLPVPCNPNDVSHGYV
TVKPGIRLHFVEMGSGPALCLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSSSP
PEIEEYAMELLCKEMVTFLDKLGIPQAVFIGHDWAGVMVWNMALFYPERVRAVASLNTPF
MPPDPDVSPMKVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRASDETGFIAVHK
ATEIGGILVNTPEDPNLSKITTEEEIEFYIQQFKKTGFRGPLNWYRNTERNWKWSCKGLG
RKILVPALMVTAEKDIVLRPEMSKNMEKWIPFLKRGHIEDCGHWTQIEKPTEVNQILIKW
LQTEVQNPSVTSKI
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| BDBM50143922 |
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| n/a |
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| Name | BDBM50143922 |
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| Synonyms: | 4-(3-Adamantan-1-yl-ureido)-butyric acid 3,7-dimethyl-oct-6-enyl ester | CHEMBL305446 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H42N2O3 |
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| Mol. Mass. | 418.6126 |
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| SMILES | [#6]-[#6](-[#6]-[#6]-[#8]-[#6](=O)-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#7]C12[#6]-[#6]-3-[#6]-[#6](-[#6]-[#6](-[#6]-3)-[#6]1)-[#6]2)-[#6]-[#6]\[#6]=[#6](/[#6])-[#6] |THB:19:20:15:18.23.17,19:18:15:20.22.21,22:14:17:20.21.19,22:20:14.23.15:17| |
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| Structure | 
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