| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 2 |
|---|
| Ligand | BDBM50578267 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2132456 (CHEMBL4841971) |
|---|
| Ki | >3000±n/a nM |
|---|
| Citation |  Konieczny, A; Conrad, M; Ertl, FJ; Gleixner, J; Gattor, AO; Grätz, L; Schmidt, MF; Neu, E; Horn, AHC; Wifling, D; Gmeiner, P; Clark, T; Sticht, H; Keller, M N-Terminus to Arginine Side-Chain Cyclization of Linear Peptidic Neuropeptide Y Y J Med Chem64:16746-16769 (2021) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Neuropeptide Y receptor type 2 |
|---|
| Name: | Neuropeptide Y receptor type 2 |
|---|
| Synonyms: | NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 42734.65 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | NPY-Y2 NPY2R HUMAN::P49146 |
|---|
| Residue: | 381 |
|---|
| Sequence: | MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSI
ILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGP
VLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLA
SPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYT
RIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDL
KEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAK
KNLEVRKNSGPNDSFTEATNV
|
|
|
|---|
| BDBM50578267 |
|---|
| n/a |
|---|
| Name | BDBM50578267 |
|---|
| Synonyms: | CHEMBL4870168 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C53H83N19O11 |
|---|
| Mol. Mass. | 1162.3468 |
|---|
| SMILES | CC(C)C[C@H](NC(=O)[C@H](CCCNC(=N)NC(=O)NCCCCN)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
