| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50404246 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_158997 (CHEMBL763924) |
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| IC50 | 84000±n/a nM |
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| Citation |  Yehia, NA; Antuch, W; Beck, B; Hess, S; Schauer-Vukasinovic, V; Almstetter, M; Furer, P; Herdtweck, E; Dömling, A Novel nonpeptidic inhibitors of HIV-1 protease obtained via a new multicomponent chemistry strategy. Bioorg Med Chem Lett14:3121-5 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
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|
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| BDBM50404246 |
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| n/a |
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| Name | BDBM50404246 |
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| Synonyms: | CHEMBL2111673 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H35NO4 |
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| Mol. Mass. | 497.6246 |
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| SMILES | C[C@H](C1C(=O)O[C@](CCc2ccccc2)(C(=O)NCc2ccc(cc2)C(C)(C)C)C1=O)c1ccccc1 |r| |
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| Structure | 
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