| Reaction Details |
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 | Report a problem with these data |
| Target | Lysine-specific demethylase 4D |
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| Ligand | BDBM50580324 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2148063 (CHEMBL5032409) |
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| IC50 | 26700±n/a nM |
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| Citation |  Nowak, RP; Tumber, A; Hendrix, E; Ansari, MSZ; Sabatino, M; Antonini, L; Andrijes, R; Salah, E; Mautone, N; Pellegrini, FR; Simelis, K; Kawamura, A; Johansson, C; Passeri, D; Pellicciari, R; Ciogli, A; Del Bufalo, D; Ragno, R; Coleman, ML; Trisciuoglio, D; Mai, A; Oppermann, U; Schofield, CJ; Rotili, D First-in-Class Inhibitors of the Ribosomal Oxygenase MINA53. J Med Chem64:17031-17050 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lysine-specific demethylase 4D |
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| Name: | Lysine-specific demethylase 4D |
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| Synonyms: | JHDM3D | JHDM3D | JMJD2D | JmjC domain-containing histone demethylation protein 3D | Jumonji domain-containing protein 2D | KDM4D | KDM4D_HUMAN | Lysine-specific demethylase 4D |
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| Type: | PROTEIN |
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| Mol. Mass.: | 58627.79 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_102441 |
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| Residue: | 523 |
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| Sequence: | METMKSKANCAQNPNCNIMIFHPTKEEFNDFDKYIAYMESQGAHRAGLAKIIPPKEWKAR
ETYDNISEILIATPLQQVASGRAGVFTQYHKKKKAMTVGEYRHLANSKKYQTPPHQNFED
LERKYWKNRIYNSPIYGADISGSLFDENTKQWNLGHLGTIQDLLEKECGVVIEGVNTPYL
YFGMWKTTFAWHTEDMDLYSINYLHLGEPKTWYVVPPEHGQRLERLARELFPGSSRGCGA
FLRHKVALISPTVLKENGIPFNRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRW
IDYGKMASQCSCGEARVTFSMDAFVRILQPERYDLWKRGQDRAVVDHMEPRVPASQELST
QKEVQLPRRAALGLRQLPSHWARHSPWPMAARSGTRCHTLVCSSLPRRSAVSGTATQPRA
AAVHSSKKPSSTPSSTPGPSAQIIHPSNGRRGRGRPPQKLRAQELTLQTPAKRPLLAGTT
CTASGPEPEPLPEDGALMDKPVPLSPGLQHPVKASGCSWAPVP
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| BDBM50580324 |
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| n/a |
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| Name | BDBM50580324 |
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| Synonyms: | CHEMBL5081435 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H10N2O4S |
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| Mol. Mass. | 290.295 |
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| SMILES | OC(=O)c1cnc(SCC(=O)c2ccccc2)[nH]c1=O |
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| Structure | 
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