| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2b |
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| Ligand | BDBM50582416 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2154525 (CHEMBL5039185) |
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| Ki | 372±n/a nM |
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| Citation |  Amelia, T; van Veldhoven, JPD; Falsini, M; Liu, R; Heitman, LH; van Westen, GJP; Segala, E; Verdon, G; Cheng, RKY; Cooke, RM; van der Es, D; IJzerman, AP Crystal Structure and Subsequent Ligand Design of a Nonriboside Partial Agonist Bound to the Adenosine A J Med Chem64:3827-3842 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2b |
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| Name: | Adenosine receptor A2b |
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| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36341.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 332 |
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| Sequence: | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
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| BDBM50582416 |
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| n/a |
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| Name | BDBM50582416 |
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| Synonyms: | CHEMBL5088305 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H13N5S |
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| Mol. Mass. | 307.373 |
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| SMILES | Nc1nc(SCc2ncc[nH]2)cc(-c2ccccc2)c1C#N |
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| Structure | 
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