| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM50582413 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2154526 (CHEMBL5039186) |
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| Ki | 347±n/a nM |
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| Citation |  Amelia, T; van Veldhoven, JPD; Falsini, M; Liu, R; Heitman, LH; van Westen, GJP; Segala, E; Verdon, G; Cheng, RKY; Cooke, RM; van der Es, D; IJzerman, AP Crystal Structure and Subsequent Ligand Design of a Nonriboside Partial Agonist Bound to the Adenosine A J Med Chem64:3827-3842 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36197.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P0DMS8 |
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| Residue: | 318 |
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| Sequence: | MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
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| BDBM50582413 |
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| n/a |
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| Name | BDBM50582413 |
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| Synonyms: | CHEMBL5078507 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H12N6S |
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| Mol. Mass. | 308.361 |
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| SMILES | Nc1nc(SCc2ncc[nH]2)nc(-c2ccccc2)c1C#N |
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| Structure | 
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