| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1A |
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| Ligand | BDBM50586501 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2168962 (CHEMBL5054021) |
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| Ki | 294±n/a nM |
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| Citation |  León, F; Obeng, S; Mottinelli, M; Chen, Y; King, TI; Berthold, EC; Kamble, SH; Restrepo, LF; Patel, A; Gamez-Jimenez, LR; Lopera-Londoño, C; Hiranita, T; Sharma, A; Hampson, AJ; Canal, CE; McMahon, LR; McCurdy, CR Activity of J Med Chem64:13510-13523 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1A |
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| Name: | 5-hydroxytryptamine receptor 1A |
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| Synonyms: | 5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A |
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| Type: | n/a |
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| Mol. Mass.: | 46122.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 422 |
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| Sequence: | MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT
RHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGN
SKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
RQ
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| BDBM50586501 |
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| n/a |
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| Name | BDBM50586501 |
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| Synonyms: | CHEMBL5072247 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H28N2O4 |
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| Mol. Mass. | 384.4687 |
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| SMILES | [H][C@@]12C[C@@H]([C@@H](CC)CN1CCc1c2[nH]c2cccc(O)c12)C(=C/OC)\C(=O)OC |r| |
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| Structure | 
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