| Reaction Details |
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 | Report a problem with these data |
| Target | Fatty-acid amide hydrolase 1 |
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| Ligand | BDBM50587454 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2172610 (CHEMBL5057744) |
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| IC50 | 220±n/a nM |
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| Citation |  Wilt, S; Kodani, S; Valencia, L; Hudson, PK; Sanchez, S; Quintana, T; Morisseau, C; Hammock, BD; Kandasamy, R; Pecic, S Further exploration of the structure-activity relationship of dual soluble epoxide hydrolase/fatty acid amide hydrolase inhibitors. Bioorg Med Chem51:0 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Fatty-acid amide hydrolase 1 |
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| Name: | Fatty-acid amide hydrolase 1 |
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| Synonyms: | Anandamide amidohydrolase | Anandamide amidohydrolase 1 | FAAH | FAAH1 | FAAH1_HUMAN | Fatty Acid Amide Hydrolase (FAAH) | Fatty-acid amide hydrolase (FAAH) | Fatty-acid amide hydrolase 1 | Oleamide hydrolase 1 |
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| Type: | Protein |
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| Mol. Mass.: | 63071.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O00519 |
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| Residue: | 579 |
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| Sequence: | MVQYELWAALPGASGVALACCFVAAAVALRWSGRRTARGAVVRARQRQRAGLENMDRAAQ
RFRLQNPDLDSEALLALPLPQLVQKLHSRELAPEAVLFTYVGKAWEVNKGTNCVTSYLAD
CETQLSQAPRQGLLYGVPVSLKECFTYKGQDSTLGLSLNEGVPAECDSVVVHVLKLQGAV
PFVHTNVPQSMFSYDCSNPLFGQTVNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGG
SIRFPSSFCGICGLKPTGNRLSKSGLKGCVYGQEAVRLSVGPMARDVESLALCLRALLCE
DMFRLDPTVPPLPFREEVYTSSQPLRVGYYETDNYTMPSPAMRRAVLETKQSLEAAGHTL
VPFLPSNIPHALETLSTGGLFSDGGHTFLQNFKGDFVDPCLGDLVSILKLPQWLKGLLAF
LVKPLLPRLSAFLSNMKSRSAGKLWELQHEIEVYRKTVIAQWRALDLDVVLTPMLAPALD
LNAPGRATGAVSYTMLYNCLDFPAGVVPVTTVTAEDEAQMEHYRGYFGDIWDKMLQKGMK
KSVGLPVAVQCVALPWQEELCLRFMREVERLMTPEKQSS
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| BDBM50587454 |
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| n/a |
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| Name | BDBM50587454 |
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| Synonyms: | CHEMBL5088092 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H18ClFN2O3S |
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| Mol. Mass. | 396.864 |
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| SMILES | Fc1ccc(NC(=O)C2CCN(CC2)S(=O)(=O)c2ccccc2Cl)cc1 |
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| Structure | 
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