| Reaction Details |
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 | Report a problem with these data |
| Target | Cholinesterase |
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| Ligand | BDBM50587755 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2185049 (CHEMBL5097131) |
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| IC50 | 3.1±n/a nM |
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| Citation |  Singh, YP; Rai, H; Singh, G; Singh, GK; Mishra, S; Kumar, S; Srikrishna, S; Modi, G A review on ferulic acid and analogs based scaffolds for the management of Alzheimer's disease. Eur J Med Chem215:0 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cholinesterase |
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| Name: | Cholinesterase |
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| Synonyms: | BCHE | Butyrylcholinesterase (BuChE) | CHLE_HORSE | Cholinesterase |
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| Type: | Enzyme |
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| Mol. Mass.: | 65643.35 |
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| Organism: | Equus caballus (Horse) |
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| Description: | P81908 |
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| Residue: | 574 |
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| Sequence: | EEDIIITTKNGKVRGMNLPVLGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSNIWNATK
YANSCYQNTDQSFPGFLGSEMWNPNTELSEDCLYLNVWIPAPKPKNATVMIWIYGGGFQT
GTSSLPVYDGKFLARVERVIVVSMNYRVGALGFLALSENPEAPGNMGLFDQQLALQWVQK
NIAAFGGNPRSVTLFGESAGAASVSLHLLSPRSQPLFTRAILQSGSSNAPWAVTSLYEAR
NRTLTLAKRMGCSRDNETEMIKCLRDKDPQEILLNEVFVVPYDTLLSVNFGPTVDGDFLT
DMPDTLLQLGQFKRTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPR
VSEFGRESILFHYMDWLDDQRAENYREALDDVVGDYNIICPALEFTRKFSELGNDAFFYY
FEHRSTKLPWPEWMGVMHGYEIEFVFGLPLERRVNYTRAEEILSRSIMKRWANFAKYGNP
NGTQNNSTRWPVFKSTEQKYLTLNTESPKVYTKLRAQQCRFWTLFFPKVLELTGNIDEAE
REWKAGFHRWNNYMMDWKNQFNDYTSKKESCSDF
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| BDBM50587755 |
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| n/a |
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| Name | BDBM50587755 |
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| Synonyms: | CHEMBL5171929 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H22BrFN2O3 |
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| Mol. Mass. | 473.335 |
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| SMILES | [Br-].COc1ccc(\C=C\C(=O)Nc2cc[n+](Cc3cccc(F)c3)cc2)cc1OC |
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| Structure | 
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