| Reaction Details |
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 | Report a problem with these data |
| Target | Glutamate receptor 3 |
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| Ligand | BDBM50158561 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_430653 (CHEMBL919618) |
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| IC50 | >100000±n/a nM |
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| Citation |  Valgeirsson, J; Nielsen, EO; Peters, D; Mathiesen, C; Kristensen, AS; Madsen, U Bioisosteric modifications of 2-arylureidobenzoic acids: selective noncompetitive antagonists for the homomeric kainate receptor subtype GluR5. J Med Chem47:6948-57 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glutamate receptor 3 |
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| Name: | Glutamate receptor 3 |
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| Synonyms: | GRIA3_RAT | Glur3 | Glutamate receptor 3 | Glutamate receptor ionotropic, AMPA 3 | Glutamate-AMPA | Gria3 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 100383.57 |
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| Organism: | RAT |
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| Description: | Glutamate-AMPA GRIA3 RAT::P19492 |
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| Residue: | 888 |
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| Sequence: | MGQSVLRAVFFLVLGLLGHSHGGFPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTE
KPFHLNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVT
PSFPTDADVQFVIQMRPALKGAILSLLSYYKWEKFVYLYDTERGFSVLQAIMEAAVQNNW
QVTARSVGNIKDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYM
LANLGFTDILLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKYT
SALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGM
TGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFVPFSDQQISNDSSSSENRTIV
VTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPE
TKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFS
FLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIF
NSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIE
SAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVR
KSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALGNAVNLAVLKLN
EQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEF
CYKSRAESKRMKLTKNTQNFKPAPATNTQNYATYREGYNVYGTESVKI
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| BDBM50158561 |
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| n/a |
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| Name | BDBM50158561 |
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| Synonyms: | 2-[3-(3-bromophenyl)ureido]-4-chlorobenzenesulfonic acid | CHEMBL224872 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H10BrClN2O4S |
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| Mol. Mass. | 405.651 |
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| SMILES | OS(=O)(=O)c1ccc(Cl)cc1NC(=O)Nc1cccc(Br)c1 |
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| Structure | 
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