| Reaction Details |
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 | Report a problem with these data |
| Target | Apelin receptor |
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| Ligand | BDBM50589282 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2193273 (CHEMBL5105633) |
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| EC50 | >150±n/a nM |
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| Citation |  Richter, JM; Alex Bates, J; Gargalovic, P; Onorato, JM; Generaux, C; Wang, T; Gordon, DA; Wexler, RR; Finlay, HJ Design and preparation of N-linked hydroxypyridine-based APJ agonists. Bioorg Med Chem Lett73:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Apelin receptor |
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| Name: | Apelin receptor |
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| Synonyms: | AGTRL1 | APJ | APJ_HUMAN | APLNR | Angiotensin receptor-like 1 | Apelin receptor | Apelin receptor (APJ) | G-protein coupled receptor APJ | G-protein coupled receptor HG11 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 42664.06 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35414 |
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| Residue: | 380 |
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| Sequence: | MEEGGDFDNYYGADNQSECEYTDWKSSGALIPAIYMLVFLLGTTGNGLVLWTVFRSSREK
RRSADIFIASLAVADLTFVVTLPLWATYTYRDYDWPFGTFFCKLSSYLIFVNMYASVFCL
TGLSFDRYLAIVRPVANARLRLRVSGAVATAVLWVLAALLAMPVMVLRTTGDLENTTKVQ
CYMDYSMVATVSSEWAWEVGLGVSSTTVGFVVPFTIMLTCYFFIAQTIAGHFRKERIEGL
RKRRRLLSIIVVLVVTFALCWMPYHLVKTLYMLGSLLHWPCDFDLFLMNIFPYCTCISYV
NSCLNPFLYAFFDPRFRQACTSMLCCGQSRCAGTSHSSSGEKSASYSSGHSQGPGPNMGK
GGEQMHEKSIPYSQETLVVD
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| BDBM50589282 |
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| n/a |
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| Name | BDBM50589282 |
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| Synonyms: | CHEMBL5208913 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H33N3O3 |
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| Mol. Mass. | 471.5906 |
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| SMILES | CCCCc1nc(O)c(C(=O)N2CC[C@@H](C2)c2ccccc2)c(O)c1N1CCCc2ccccc12 |r| |
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| Structure | 
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